This gene encodes a member of the FXYD-domain family of small membrane proteins, characterized by a 35-amino acid signature sequence starting with PFXYD, containing 7 invariant and 6 highly conserved amino acids. The FXYD family regulates ion transport and includes proteins like FXYD1 (phospholemman), FXYD2 (gamma subunit of Na,K-ATPase), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC), which induce channel activity in expression systems. Transmembrane topology for FXYD1 and FXYD2 shows the N-terminus extracellular and C-terminus cytoplasmic. FXYD7, a novel gene product, has not been characterized as a protein. The sequence is validated by similar human genomic data.